Protocols – Diagnosis, Treatment and Follow-Up

The data specified below were provided by the hospitals.
It is the mother’s responsibility to contact the hospital in which she intends to give birth and check the up-to-date protocol

No information received

Postnatal Diagnosis Protocol:

Type of newborn test to identify infection

For infants with suspected infection (clinical findings or known infection during pregnancy), a urine test will be performed.
All other infants are screened through universal saliva screening, and if they test positive for CMV, a urine test will be performed for confirmation.

The protocol of the newborn tests when there is known infection in amniotic fluid

After birth, during hospitalization, the following tests and evaluations are performed: a complete blood count and blood chemistry tests, a brain ultrasound, an eye examination, hearing screening, and consultation with a pediatric infectious disease specialist.

An appointment for a Bera test at the hearing institute is scheduled between two weeks and one month after birth.

The protocol of the newborn tests when there is known maternal infection during pregnancy, but amniocentesis was not performed
This protocol is identical to the protocol used when the amniotic fluid test is positive.

Newborn saliva/urine test when there is known negative amniocentesis
Yes, certainly with regard to the initial evaluation. However, the intervals between long-term follow-up visits are extended thereafter.

The follow-up and treatment protocol of asymptomatic CMV children:

Until what age is follow-up conducted?
Follow-up visits are conducted at more frequent intervals during the first year of life, followed by annual visits until the age of five.

What tests are performed in the protocol and how frequently?

Tests and follow-up visits are conducted at the CMV clinic.

The frequency is every 3-6 months and is determined according to whether the timing of the infection during pregnancy is known.

The follow-up and treatment protocol of symptomatic CMV children:

Until what age is follow-up conducted?
Close follow-up at the CMV clinic, hearing tests, and consultations with a pediatric neurologist are provided for as long as the patient is receiving antiviral treatment. Afterwards, the intervals between follow-up visits are extended..

What tests are performed in the protocol and how frequently?
See the details above.

Duration of drug therapy
The duration of treatment ranges from 6 months to one year.

Postnatal Diagnosis Protocol:

Type of newborn test to identify infection
Urine test

 The protocol of the newborn tests when there is known infection in amniotic fluid
During hospitalization, the following are performed: Blood tests, brain ultrasound, eye fundus examination, BERA test will be performed at the Lin Medical Center or at the patient’s HMO, initial consultation with a pediatric infectious diseases specialist is conducted in the department.

The protocol of the newborn tests when there is known maternal infection during pregnancy, but amniocentesis was not performed
Yes

Newborn saliva/urine test when there is known negative amniocentesis
Yes

The follow-up and treatment protocol of asymptomatic and symptomatic CMV children:
The follow-up protocol is not conducted at Carmel Medical center. The newborns are referred to infectious disease clinics that are responsible for the follow-up and treatment of infants with congenital CMV infection.

No information received

No information received

Postnatal Diagnosis Protocol:

Type of newborn test to identify infection
Saliva test + urine test if the saliva test is positive

The protocol of the newborn tests when there is known infection in amniotic fluid
During hospitalization, the following are performed: Blood tests, brain ultrasound, eye fundus examination, BERA test

The protocol of the newborn tests when there is known maternal infection during pregnancy, but amniocentesis was not performed
No information received

Newborn saliva/urine test when there is known negative amniocentesis
No information received

The follow-up and treatment protocol of asymptomatic CMV children:

Until what age is follow-up conducted?
No information received

What tests are performed in the protocol and how frequently?
No information received

 The follow-up and treatment protocol of asymptomatic CMV children:

Until what age is follow-up conducted?
No information received

What tests are performed in the protocol and how frequently?
No information received

Duration of drug therapy
No information received

Postnatal Diagnosis Protocol:

Type of newborn test to identify infection
Urine test

The protocol of the newborn tests when there is known infection in amniotic fluid
During hospitalization, the following are performed: Blood tests, brain ultrasound, eye fundus examination, consultation with pediatric infectious diseases specialist, a BERA test appointment will be scheduled.

Upon discharge, appointments will also be scheduled for Otolaryngology Clinic, Neurology Clinic and Pediatric Infectious Diseases Clinic.

.The protocol of the newborn tests when there is known maternal infection during pregnancy, but amniocentesis was not performed
The tests are performed only if the urine test is positive. If a newborn was discharged home and the test comes back positive, the staff assures the tests are completed as soon as possible.

Newborn saliva/urine test when there is known negative amniocentesis
Yes

The follow-up and treatment protocol of asymptomatic CMV children:

Until what age is follow-up conducted?
No information received

What tests are performed in the protocol and how frequently?
No information received

The follow-up and treatment protocol of symptomatic CMV children:

Until what age is follow-up conducted?
No information received

What tests are performed in the protocol and how frequently?
No information received

Duration of drug therapy
No information received

 Postnatal Diagnosis Protocol:

Type of newborn test to identify infection
Urine test

The protocol of the newborn tests when there is known infection in amniotic fluid
During hospitalization, the following are performed: Blood tests, brain ultrasound, eye fundus examination, BERA test

The protocol of the newborn tests when there is known maternal infection during pregnancy, but amniocentesis was not performed
Mostly Yes, with family consent

Newborn saliva/urine test when there is known negative amniocentesis
Yes

The follow-up and treatment protocol of asymptomatic CMV children:

Until what age is follow-up conducted?
No information received

What tests are performed in the protocol and how frequently?
No information received

The follow-up and treatment protocol of symptomatic CMV children:

Until what age is follow-up conducted?
No information received

What tests are performed in the protocol and how frequently?
No information received

Duration of drug therapy
No information received

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